Prion Protein (PrP) and namely its abnormal isoform, partially resistant to proteinase K (PrPres), is the only specific molecular marker of the Transmissible Spongiform Encephalopathies (TSEs) such as Bovine Spongiform Encephalopathie (BSE) or its huma...More
|Stability||Store at -20degrees;shelf life 2 years maximum after production|
|Antigen||This anti-Prion Protein Monoclonal Antibody was raised against a preparation of SAF (scrapie associated fibrils) from infected hamster brain.|
|Label||Labelling upon request|
Reconstitute the content of the vial in 1 mL of water.
For immunohistochemistry, EIA and flow cytometry, the optimal working must be determined empirically (currently between 0.1 and 1 µg/mL). For western blot analysis of PrPc, dilute to a final concentra
|Application Media||Reconstitute the content of the vial in 1 mL of water.|
|Formulation||lyophilized IgG with BSA|
Haeberlé A.M. et al. Synaptic Prion Protein Immuno-Reactivity in the Rodent Cerebellum. Microscopy research and Technique 50:66-75 (2000).
Vincent B., et al. Phorbol Ester-regulated Cleavage of Normal Prion Protein in HEK293 Human Cells and Murine Neurons