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- Prion Protein Monoclonal Antibody - BAR 233
Prion Protein Monoclonal Antibody - BAR 233
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Cat No: A03223
Antibodies
- Monoclonal Antibodies
Prion Protein (PrP) and namely its abnormal isoform, partially resistant to proteinase K (PrPres), is the only specific molecular marker of the Transmissible Spongiform Encephalopathies (TSEs) such as Bovine Spongiform Encephalopathie (BSE) or its huma...
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Territorial Availability: Available worldwide directly through Bertin or your local distributor
Synonyms:
- Prion Protein Monoclonal Antibody - BAR 233
Correlated keywords:
- proteins
- mad
- cow
- diseases
- bovine
- spongiform
- encephalopathy
- scrapie
Product Overview:
Prion Protein (PrP) and namely its abnormal isoform, partially resistant to proteinase K (PrPres), is the only specific molecular marker of the Transmissible Spongiform Encephalopathies (TSEs) such as Bovine Spongiform Encephalopathie (BSE) or its human form, the New Variant of Creutzfeld-Jakob disease.
This antibody recognises the protein sequence within amino acids 141-152 (human numbering).
Prion Protein (PrP) and namely its abnormal isoform, partially resistant to proteinase K (PrPres), is the only specific molecular marker of the Transmissible Spongiform Encephalopathies (TSEs) such as Bovine Spongiform Encephalopathie (BSE) or its human form, the New Variant of Creutzfeld-Jakob disease.
This antibody recognises the protein sequence within amino acids 141-152 (human numbering).
| Size | 200 µg |
| Shipping | Dry Ice |
| Host | Mouse |
| Antigen | This anti-Prion Protein Monoclonal Antibody was raised against an ovine recombinant protein. |
| Clone | BAR233 |
| Isotype | IgG2b |
| Application(s) | Reconstitute the content of the vial in 1 mL of water. For western blot analysis of PrPc, dilute to a final concentration of 1 µg/mL and use BSA as blocking reagent. For EIA and flow cytometry, the optimal working must be determined empirically (currently between 0.1 and 1 µg/mL). |
| Specificity | |
| Application Media | Reconstitute the content of the vial in 1 mL of water. |
| Formulation | lyophilized IgG with BSA |
| Custom Code | 3822000000 |
| UNSPSC code | 12352203 |
Féraudet C., et al. Screening of 145 Anti-PrP Monoclonal Antibodies for Their Capacity to Inhibit PrPSc Replication in Infected Cells. The journal of Biological Chemistry. Vol. 280. No. 12, March 25, pp. 11247-11258, 2005.
Selective and Efficient Immunoprecipitation of the Disease-associated Form of the Prion Protein Can Be Mediated by Nonspecific Interactions between Monoclonal Antibodies and Scrapie-associated Fibrils.The journal of Biological Chemistry. Vol. 279. No. 29, July 16, pp. 30143-30149, 2004.
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