Prion Protein (PrP) and namely its abnormal isoform, partially resistant to proteinase K (PrPres), is the only specific molecular marker of the Transmissible Spongiform Encephalopathies (TSEs) such as Bovine Spongiform Encephalopathie (BSE) or its huma...More
|Antigen||This anti Prion Protein Monoclonal Antibody was raised against a preparation of SAF (scrapie associated fibrils) from infected hamster brain.|
Reconstitute the content of the vial in 1 mL of water.
For immunohistochemistry, the optimal working dilution must be determined empirically (currently between 0.1 and 1 µg/mL). For western blot analysis of PrPc, dilute the antibody to a final concentration of 1 µg/mL.
|Application Media||Reconstitute the content of the vial in 1 mL of water.|
|Formulation||lyophilized IgG with BSA|
Demart S., et al. New Insight into Abnormal Prion Protein Using Monoclonal Antibodies. Biochemical and Biophysical Research Communications 265, 652-657 (1999).