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- Prion Protein Monoclonal Antibody - SAF 70
Prion Protein Monoclonal Antibody - SAF 70
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Cat No: A03206
Antibodies
- Monoclonal Antibodies
Prion Protein (PrP) and namely its abnormal isoform, partially resistant to proteinase K (PrPres), is the only specific molecular marker of the Transmissible Spongiform Encephalopathies (TSEs) such as Bovine Spongiform Encephalopathie (BSE) or its huma...
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Territorial Availability: Available worldwide directly through Bertin or your local distributor
Synonyms:
- Prion Protein Monoclonal Antibody - SAF 70
Correlated keywords:
- proteins
- mad
- cow
- diseases
- bovine
- spongiform
- encephalopathy
- scrapie
Product Overview:
Prion Protein (PrP) and namely its abnormal isoform, partially resistant to proteinase K (PrPres), is the only specific molecular marker of the Transmissible Spongiform Encephalopathies (TSEs) such as Bovine Spongiform Encephalopathie (BSE) or its human form, the New Variant of Creutzfeld-Jakob disease.
This antibody recognises the protein sequence within amino acids 142-160 (human numbering).
Prion Protein (PrP) and namely its abnormal isoform, partially resistant to proteinase K (PrPres), is the only specific molecular marker of the Transmissible Spongiform Encephalopathies (TSEs) such as Bovine Spongiform Encephalopathie (BSE) or its human form, the New Variant of Creutzfeld-Jakob disease.
This antibody recognises the protein sequence within amino acids 142-160 (human numbering).
| Size | 200 µg |
| Shipping | Dry Ice |
| Host | Mouse |
| Antigen | This anti-Prion Protein Monoclonal Antibody was raised against a preparation of SAF (scrapie associated fibrils) from infected hamster brain. |
| Clone | SAF 70 |
| Isotype | IgG2b |
| Application(s) | Reconstitute the content of the vial in 1 mL of water. For western blot analysis of PrPc, dilute the antibody to a final concentration of 1 µg/mL. |
| Specificity | |
| Application Media | Reconstitute the content of the vial in 1 mL of water. |
| Formulation | lyophilized IgG with BSA |
| Custom Code | 3822000000 |
| UNSPSC code | 12352203 |
Nishida N., et al. Successful Transmission of Three Mouse-Adapted Scrapie Strains to Murine Neuroblastoma Cell Lines Overrexpressing Wild-Type Mouse Prion Protein. Journal of Virology 320-325 (January 2000).
Vincent B., et al. Phorbol Ester-regulated Cleavage of Normal Prion Protein in HEK293 Human Cells and Murine Neurons. The journal of Biological Chemistry. Vol. 275, No 45, Issue of November 10, pp.35612-35616 (2000).
Demart S., et al. New Insight into Abnormal Prion Protein Using Monoclonal Antibodies.Biochemical and Biophysical Research Communications 265, 652-657 (1999).
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