Prion Protein (PrP) and namely its abnormal isoform, partially resistant to proteinase K (PrPres), is the only specific molecular marker of the Transmissible Spongiform Encephalopathies (TSEs) such as Bovine Spongiform Encephalopathie (BSE) or its huma...More
|Antigen||This anti-Prion Protein Monoclonal Antibody was raised against a human recombinant protein.|
Reconstitute the content of the vial in 1 mL of water.
For immunohistochemistry, the optimal working dilution must be determined empirically (currently between 0.1 and 1 µg/mL). For western blot analysis of PrPc, dilute the antibody to a final concentration of 1 µg/mL.
|Application Media||Reconstitute the content of the vial in 1 mL of water.|
|Formulation||lyophilized IgG with BSA|
Krasemann S. et al. Generation of monoclonal antibodies against prion proteins with an unconventional nucleic acid-based immunization strategy. Journal of Biotechnology 73, 119-129 (1999).
Krasemann S. et al. Induction of antibodies against human prion proteins (PrP) by DNA-mediated immunization of PrP 0/0 mice. Journal of Immunological Methods 199, 109-118 (1996).
Krasemann S. et al. Generation of monoclonal antibody against Human prion proteins in PrP 0/0 Mice.
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