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13,14-dihydro-15-keto Prostaglandin E2-d4

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    13,14-<wbr/>dihydro-<wbr/>15-<wbr/>keto Prostaglandin E<sub>2</sub>-<wbr/>d<sub>4</sub>
  • 13,14-<wbr/>dihydro-<wbr/>15-<wbr/>keto Prostaglandin E<sub>2</sub>-<wbr/>d<sub>4</sub>
Cat No: 10010606
Biochemicals - Isotopically Labeled Standards

13,14-dihydro-15-keto Prostaglandin E2-d4 (13,14-dh-15-keto PGE2-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 13,14-dh-15-keto PGE2 (Item No. 14650) by GC...


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Territorial Availability: Available through Bertin Technologies only in France
  • 9,15-dioxo-11?-hydroxy-prost-5Z-en-1-oic-3,3,4,4-d4 acid
Correlated keywords:
  • deuterated metabolites 13,14-dihydro-15-keto-PGE2 prostaglandins PGE2 deuterium
Product Overview:
13,14-dihydro-15-keto Prostaglandin E2-d4 (13,14-dh-15-keto PGE2-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 13,14-dh-15-keto PGE2 (Item No. 14650) by GC- or LC-MS. 13,14-dh-15-keto PGE2 is the primary metabolite of PGE2 (Item No. 14010) in plasma.{182} Endogenous or infused PGE2 is rapidly metabolized by the enzymes 15-hydroxy PGDH and 15-oxo-PG Δ13-reductase to form 13,14-dh-15-keto PGE2. 13,14-dh-15-keto PGE2 accumulates to detectable levels; plasma levels in humans are between 10-100 pg/ml.{433,4383} It undergoes further metabolism and chemical decomposition, giving it a relatively short half-life. In dogs, the plasma half-life of 13,14-dh-15-keto PGE2 is about 9 minutes.{433} In humans the metabolite has a similar short half-life, making it a poor choice of analytes for assays designed to measure total PGE2 biosynthesis.{366,581}
Size 25 µg
Shipping dry ice
Molecular Formula C20H28D4O5
SMILES O[C@H]1[C@H](CCC(CCCCC)=O)[C@@H](C/C=C\C([2H])([2H])C([2H])([2H])CC(O)=O)C(C1)=O
Molecular Weight 356,5
Formulation A solution in methyl acetate
Purity ≥99% deuterated forms (d1-d4)
Custom Code 3822.19
UNSPSC code 12352100

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