Prostaglandin E2-1-glyceryl este

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Prostaglandin E₂-1-glyceryl ester-d₅

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Cat No: 10004197

Biochemicals - Isotopically Labeled Standards

Prostaglandin E2-1-glyceryl ester-d5 (PGE2-1-glyceryl ester-d5) contains five deuterium atoms. It is intended for use as an internal standard for the quantification of PGE2-1-glyceryl ester by GC- or LC-mass spectrometry. 2-Arachidonoyl glycerol (2-AG)...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

9-oxo-11?,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid,1-glyceryl ester-d5

Correlated keywords:

standards deuterium internal isotopes GC/MS GC-MS LC/MS LC-MS mass spectrometry deuterated prostaglandins PGs PGE2-1-GE esters 2-AG 2-arachidonyl-glycerol metabolites COX-2 PGHS-2 cycloxygenases synthases PGE2-2-GE COX2 PGHS2 cannabinoids cbs synthetic 37497-47-5

Product Overview:
Prostaglandin E2-1-glyceryl ester-d5 (PGE2-1-glyceryl ester-d5) contains five deuterium atoms. It is intended for use as an internal standard for the quantification of PGE2-1-glyceryl ester by GC- or LC-mass spectrometry. 2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the central cannabinoid receptor.{4614,5306} Incubation of 2-AG with cyclooxygenase-2 and specific PGH2 isomerases in cell cultures and isolated enzyme preparations results in PG glycerol ester formation.{11045} The biosynthesis of PGH, PGD, PGE, PGF, and thromboxane A-2-glyceryl ester compounds have all been documented. The 2-glyceryl ester moiety equilibrates rapidly (within minutes) with the more stable 1-glyceryl ester, producing a 10:90 2:1-glyceryl ester mixture in typical aqueous media. While the stability and metabolism of these prostaglandin products has been investigated, little is known about their intrinsic biological activity.{10555}

Size	50 µg
Shipping	dry ice
Molecular Formula	C₂₃H₃₃D₅O₇
SMILES	O=C1[C@H](C/C=C\CCCC(OC([2H])([2H])C(O)([2H])C([2H])([2H])O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1
Molecular Weight	431,6
Formulation	A solution in acetonitrile
Purity	≥99% deuterated forms (d1-d5)
Custom Code	3822.19
UNSPSC code	12352100

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

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