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Prostaglandin E2-1-glyceryl ester

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    Prostaglandin E<sub>2</sub>-<wbr/>1-<wbr/>glyceryl ester
  • Prostaglandin E<sub>2</sub>-<wbr/>1-<wbr/>glyceryl ester
Cat No: 10140
Biochemicals - Lipids
Cayman
€95.00
Price is excluding VAT and does not include packaging neither shipping

2-Arachidonoyl glycerol (2-AG; Item No. 62160) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor.{4614,5306} Incubation of 2-AG with cyclooxygenase-2 and specific prostaglandin ...

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This product can only be bought through Cayman Chemical. Please contact us.

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Territorial Availability: Available through Bertin Pharma only in Europe
Synonyms:
  • 9-oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid, 1-glyceryl ester
Correlated keywords:
  • prostaglandins PGs PGE2-1-GE esters 2-AG 2-arachidonyl-glycerol metabolites COX-2 PGHS-2 cycloxygenases synthases PGE2-2-GE COX2 PGHS2 cannabinoids cbs synthetic
Product Overview:
2-Arachidonoyl glycerol (2-AG; Item No. 62160) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor.{4614,5306} Incubation of 2-AG with cyclooxygenase-2 and specific prostaglandin H2 (PGH2) isomerases in cell cultures and isolated enzyme preparations results in prostaglandin glycerol ester formation.{11045} The biosynthesis of PGH, PGD, PGE, PGF, and Thromboxane A-2-glyceryl ester compounds have all been documented. The 2-glyceryl ester moiety equilibrates rapidly (within minutes) with the more stable 1-glyceryl ester, producing a 10:90 2:1-glyceryl ester mixture in typical aqueous media. While the stability and metabolism of these prostaglandin products has been investigated, little is known about their intrinsic biological activity.{10555}
Size 1 mg
Shipping dry ice
Stability Store at -80 degrees; shelf life 365 days
CAS Number 37497-47-5
Molecular Formula C23H38O7
SMILES CCCCCC(O)/C=C/[C@H]1C(O)CC(=O)C1C/C=C\CCCC(=O)OCC(O)CO
Molecular Weight 426,6
Formulation A solution in ethanol
Purity ≥98% (as a 85:15 mixture of the 1- and 2-glyceryl esters)
Custom Code 2937.50
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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ISO Guide 34:2009

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