Confirm delete?

Bertin Bioreagent
logo
All categories
Contact Us
You are here :

13,14-dihydro-15-keto Prostaglandin E2-d4 MaxSpec® Standard

  • Zoom
    13,14-<wbr/>dihydro-15-<wbr/>keto Prostaglandin E<sub>2</sub>-d<sub>4</sub> MaxSpec<sup>®</sup> Standard
  • 13,14-<wbr/>dihydro-15-<wbr/>keto Prostaglandin E<sub>2</sub>-d<sub>4</sub> MaxSpec<sup>®</sup> Standard
Cat No: 25372
Biochemicals - Analytical Standards
Cayman

13,14-dihydro-15-keto Prostaglandin E2-d4 (13,14-dh-15-keto PGE2-d4) is intended for use as an internal standard for the quantification of 13,14-dh-15-keto PGE2 (Item No. 14650) by GC- or LC-MS. 13,14-dh-15-keto PGE2 is the primary metabolite of PGE2 ...

More
: 10 µg

This product can only be bought through Cayman Chemical. Please contact us.

Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • 9,15-dioxo-11?-hydroxy-prost-5Z-en-1-oic-3,3,4,4-d4 acid
Correlated keywords:
  • deuterated deuterium quantitative standard mass Max spec spectrometry lipidomics LC-MS LCMS
Product Overview:
13,14-dihydro-15-keto Prostaglandin E2-d4 (13,14-dh-15-keto PGE2-d4) is intended for use as an internal standard for the quantification of 13,14-dh-15-keto PGE2 (Item No. 14650) by GC- or LC-MS. 13,14-dh-15-keto PGE2 is the primary metabolite of PGE2 (Item No. 14010) in plasma.{182} Endogenous or infused PGE2 is rapidly metabolized by the enzymes 15-hydroxy PGDH and 15-oxo-PG Δ13-reductase to form 13,14-dh-15-keto PGE2. 13,14-dh-15-keto PGE2 accumulates to detectable levels; plasma levels in humans are between 10-100 pg/ml.{433,4383} It undergoes further metabolism and chemical decomposition, giving it a relatively short half-life. In dogs, the plasma half-life of 13,14-dh-15-keto PGE2 is about 9 minutes.{433} In humans the metabolite has a similar short half-life, making it a poor choice of analytes for assays designed to measure total PGE2 biosynthesis.{366,581} 13,14-dh-15-keto PGE2-d4 MaxSpec® standard is a quantitative grade standard of 13,14-dh-15-keto PGE2-d4 (Item No. 10010606) that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This 13,14-dh-15-keto PGE2-d4 MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.
Size 10 µg
Shipping dry ice
Molecular Formula C20H28D4O5
SMILES O=C1[C@H](C/C=C\C([2H])([2H])C([2H])([2H])CC(O)=O)[C@@H](CCC(CCCCC)=O)[C@H](O)C1
Molecular Weight 356,5
Formulation A solution in methyl acetate at 10 µg/ml
Purity ≥95%
Custom Code 3822.19
UNSPSC code 12352100

Click here to ask for your quote and get 15% off Cayman's products.

 

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

/ We also advise you

Cross selling for this product : 13,14-<wbr/>dihydro-15-<wbr/>keto Prostaglandin E<sub>2</sub>-d<sub>4</sub> MaxSpec<sup>®</sup> Standard There are 3 products.

Search