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Prazosin (hydrochloride)

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    Prazosin (hydro<wbr>chloride)
  • Prazosin (hydro<wbr>chloride)
Cat No: 15023
Biochemicals - Receptor Pharmacology
Cayman
€33.00
Price is excluding VAT and does not include packaging neither shipping

Prazosin is an antihypertensive agent that blocks postsynaptic α1-adrenergic receptors in the periphery (IC50 = 0.20 nM in dog aorta) and is capable of crossing the blood-brain barrier, decreasing sympathetic outflow in the brain (IC50 = 1.7 nM in rat...

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This product can only be bought through Cayman Chemical. Please contact us.

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Territorial Availability: Available through Bertin Technologies only in Europe
Synonyms:
  • [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-furanyl-methanone, monohydrochloride
Correlated keywords:
  • 86126-06-9 19216-56-9 Hypertensions α1-adrenergic receptors antagonists melatonin MT3 HCl antihypertensives anti-hypertensivesanti hypertensives agents blocks blocking postsynaptic alpha1 a1 .alpha.1 a1-adrenergic alpaha1-adrenergic .alpaha.1-adrenergic α1 periphery blood brains barriers blood-brains adverszuten alpress LP CP 12299-1 CPs 12299-1 CP-12299-1 CP-122991 CP122991 CP12299-1 deprazolin duramipress eurex hypovase hypovasole minipress NSCs 292810 NSC292810 peripress pratsiol furazosin sinetens dogs aortas hearts sympathetic outflow rats hamsters Adversuten
Product Overview:
Prazosin is an antihypertensive agent that blocks postsynaptic α1-adrenergic receptors in the periphery (IC50 = 0.20 nM in dog aorta) and is capable of crossing the blood-brain barrier, decreasing sympathetic outflow in the brain (IC50 = 1.7 nM in rat brain).{22637,22636} Prazosin is also a potent antagonist at the melatonin MT3 receptor (Ki = 10.2 - 12.4 nM; IC50 = 7.8 nM in hamster).{22638,22635}
Size 50 mg
Shipping dry ice
Stability Store at -20 degrees; shelf life 730 days
CAS Number 19237-84-4
Molecular Formula C19H21N5O4 • HCl
SMILES COC(C(OC)=C1)=CC2=C1C(N)=NC(N3CCN(C(C4=CC=CO4)=O)CC3)=N2.Cl
Molecular Weight 419,9
Formulation A crystalline solid
Purity ≥98%
Custom Code 2922.19
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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