5-trans-17-phenyl trinor Prostag

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5-trans-17-phenyl trinor Prostaglandin F_2? ethyl amide

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Cat No: 10008132

Biochemicals - Lipids

17-phenyl trinor Prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide) is an F-series PG analog which has been approved for use as an ocular hypotensive drug.{8941} 5-trans-17-phenyl trinor PGF2α ethyl amide is an isomer of 17-phenyl trin...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

N-ethyl-9?,11?,15S-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5E,13E-dien-1-amide

Correlated keywords:

isomers impurity intraocular pressure lumigan prostaglandins hypotensive agonists IOPs glaucoma PGF2a PGF2? PGs

Product Overview:
17-phenyl trinor Prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide) is an F-series PG analog which has been approved for use as an ocular hypotensive drug.{8941} 5-trans-17-phenyl trinor PGF2α ethyl amide is an isomer of 17-phenyl trinor PGF2α ethyl amide wherein the double bond between carbons 5 and 6 has been changed from cis (Z) to trans (E). The trans isomer of 17-phenyl trinor PGF2α ethyl amide occurs as an impurity in commercial preparations of the bulk drug product. The present compound was prepared primarily as an analytical standard for detection and quantitation of this impurity. From what can be inferred from the study of other trans isomers of F-type PGs, the biological activity of this isomer is likely to be similar to that of the cis isomer. However, there are no specific published reports on the biological activity of 5-trans-17-phenyl trinor PGF2α ethyl amide.

Size	1 mg
Shipping	dry ice
CAS Number	1163135-95-2
Molecular Formula	C₂₅H₃₇NO₄
SMILES	O[C@@H]1[C@H](C/C=C/CCCC(NCC)=O)[C@@H](/C=C/[C@@H](O)CCC2=CC=CC=C2)[C@H](O)C1
Molecular Weight	415,6
Formulation	A solution in methyl acetate
Purity	≥98%
Custom Code	3822.19
UNSPSC code	12352100

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