17-phenyl trinor Prostaglandin F

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17-phenyl trinor Prostaglandin F_2? ethyl amide

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Cat No: 16820

Biochemicals - Lipids

17-phenyl trinor Prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide) is an F-series PG analog which has been approved for use as an ocular hypotensive drug.{8941} Investigations in our lab have shown that 17-phenyl trinor PGF2α ethyl am...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

N-ethyl-9?,11?,15S-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-amide

Correlated keywords:

lumigan prostaglandins N-ethylamides intraocular hypotensive agonists IOP glaucoma 17-phenyl-trinor-pgf2alpha-ethylamide 17-phenyl-trinor-pgf2a-ethylamide 17-phenyl-trinor-pgf2.alpha.-ethylamide FP receptors ophthalmology

Product Overview:
17-phenyl trinor Prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide) is an F-series PG analog which has been approved for use as an ocular hypotensive drug.{8941} Investigations in our lab have shown that 17-phenyl trinor PGF2α ethyl amide is converted by an amidase enzymatic activity in the bovine and human cornea to yield the corresponding free acid, with a conversion rate of about 40 µg/g corneal tissue/24 hours.{9311} The free acid, 17-phenyl trinor PGF2α, is a potent FP receptor agonist.{2058,1374} In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity.

Size	1 mg
Shipping	dry ice
CAS Number	155206-00-1
Molecular Formula	C₂₅H₃₇NO₄
SMILES	CCN([H])C(CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)CCC2=CC=CC=C2)[C@H](O)C[C@@H]1O)=O
Molecular Weight	415,6
Formulation	A crystalline solid
Purity	≥97%
Custom Code	2937.50
UNSPSC code	12352100

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Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

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17-phenyl trinor Prostaglandin F2? ethyl amide