Rp-Cyclic AMPS (triethylammonium

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Rp-Cyclic AMPS (triethylammonium salt)

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Cat No: 16985

Biochemicals - Kinase Inhibitors

Rp-Cyclic AMPS (Rp-cAMPS) is a non-hydrolyzable phosphorothioate analog of cAMP.{26216} It is a competitive inhibitor of cAMP-dependent protein kinases I and II (IC50s = 12.5 and 4.5 µM, respectively).{27707,27705} Rp-cAMPS is not hydrolyzed by bovine...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

cyclic 3',5'-[hydrogen (R)-phosphorothioate] adenosine, triethylammonium salt

Correlated keywords:

73208-40-9 biochemical inhibitor kinase protein intracellular signaling nucleotide cell biology inhibit non-hydrolyzable phosphorothioate analog cAMP competitive cAMP-dependent I II hydrolyzed yeast phosphodiesterase research in vitro vivo nonhydrolyzable cyclic AMP adenosine monophosphate monophosphorothioate

Product Overview:
Rp-Cyclic AMPS (Rp-cAMPS) is a non-hydrolyzable phosphorothioate analog of cAMP.{26216} It is a competitive inhibitor of cAMP-dependent protein kinases I and II (IC50s = 12.5 and 4.5 µM, respectively).{27707,27705} Rp-cAMPS is not hydrolyzed by bovine heart cAMP phosphodiesterase but can be hydrolyzed by yeast phosphodiesterase.{27706} It is broadly used in research involving cAMP-dependent signaling in vitro and in vivo.{26216,26217,26218}

Size	500 µg
Shipping	dry ice
CAS Number	151837-09-1
Molecular Formula	C₁₀H₁₁N₅O₅PS • C₆H₁₆N
SMILES	O[C@H]1[C@H](N2C=NC3=C2N=CN=C3N)O[C@H]4[C@H]1O[P@@](OC4)([S-])=O.CC[NH+](CC)CC
Molecular Weight	446,5
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2933.49
UNSPSC code	12352100

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Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

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