5-Methyltetrahydrofolic Acid (hy

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5-Methyltetrahydrofolic Acid (hydrate)

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Cat No: 16159

Biochemicals - More Biochemicals

5-Methyltetrahydrofolic acid is a biologically active form of folic acid that functions, in conjunction with vitamin B12, as a methyl-group donor involved in the conversion of homocysteine to methionine.{26617,26619} The availability of methyl groups ...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

N-[4-[[(2-amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid, hydrate

Correlated keywords:

folic acid folate vitamins B methyl groups donors homocysteine nitric oxide cardiovascular risks methionine metabolism 5MTHF 5 MTHF B12 methylation synthesis DNA neural tubes closures activity hypercholesterolemia hyperhomocysteinemia vascular endothelial N5-methyltetrahydropteroylglutamate N5-methyltetrahydrofolic N5 methyltetrahydropteroylglutamate methyltetrahydrofolic 3922-58-5 76937-22-9 134-35-0

Product Overview:
5-Methyltetrahydrofolic acid is a biologically active form of folic acid that functions, in conjunction with vitamin B12, as a methyl-group donor involved in the conversion of homocysteine to methionine.{26617,26619} The availability of methyl groups is essential for a variety of methylation reactions including the synthesis of DNA and proper neural tube closure.{26617} It has been used to restore nitric oxide-generating activity in cases of familial hypercholesterolemia or hyperhomocysteinemia, reducing homocysteine levels and improving vascular endothelial function.{6542,26618}

Size	1 mg
Shipping	dry ice
Molecular Formula	C₂₀H₂₅N₇O₆ • XH₂O
SMILES	O=C1C2=C(NCC(CNC3=CC=C(C(N[C@H](C(O)=O)CCC(O)=O)=O)C=C3)N2C)NC(N)=N1.O
Molecular Weight	459,5
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2922.19
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.