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Levomefolate (calcium salt hydrate)

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    Levomefolate (calcium salt hydrate)
  • Levomefolate (calcium salt hydrate)
Cat No: 21616
Biochemicals - More Biochemicals
Cayman

Levomefolate is the calcium salt of 5-methyltetrahydrofolic acid (Item No. 16159), a biologically active form of folic acid (Item No. 20515) that functions, in conjunction with Vitamin B12 (Item No. 18425), as a methyl-group donor involved in the conv...

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This product can only be bought through Cayman Chemical. Please contact us.

Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • N-[4-[[[(6S)-2-amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-L-glutamic acid, monocalcium salt, hydrate
Correlated keywords:
  • 151533-22-1 31690-09-2 L-methylfolate bodyfolin deplin metafolin nutrifolin methyltetrahydrofolate MTHF bay867660
Product Overview:
Levomefolate is the calcium salt of 5-methyltetrahydrofolic acid (Item No. 16159), a biologically active form of folic acid (Item No. 20515) that functions, in conjunction with Vitamin B12 (Item No. 18425), as a methyl-group donor involved in the conversion of homocysteine to methionine.{26617,26618} The availability of methyl groups is essential for a variety of methylation reactions including the synthesis of DNA and proper neural tube closure.{26617} Levomefolate is included in formulations of certain oral contraceptives to ensure adequate folic acid levels in women of child-bearing age to reduce the risk of neural tube defects. The combination of levomefolate and oral contraceptives increases folic acid levels.{34150,34149}
Size 500 mg
Shipping dry ice
Molecular Formula C20H23N7O6 • Ca [XH2O]
SMILES O=C1C2=C(NC[C@H](CNC3=CC=C(C(N[C@H](C([O-])=O)CCC([O-])=O)=O)C=C3)N2C)NC(N)=N1.[Ca+2].O
Molecular Weight 497,5
Formulation A crystalline solid
Purity ≥98%
Custom Code 2916.39
UNSPSC code 12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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