Ganglioside GQ1b Mixture (sodium

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Ganglioside G_Q1b Mixture (sodium salt)

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Cat No: 15589

Biochemicals - Lipids

Ganglioside GQ1b is a tetrasialoganglioside that contains two sialic acid residues linked to an inner galactose unit. It stimulates phosphorylation of several ecto-type protein kinase substrates on the surface of GOTO human neuroblastoma cells when us...

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Correlated keywords:

lipids ceramides gangliosides glycosphingolipids sialic acids oligosaccharides microdomains rafts tetrasialogangliosides differentiation neurons neurites ERK1/2 MAPK MAP Kinases signaling ecto-type proteins phosphorylation keratinocytes ecto types cell-surface cells surfaces neuronal systems intracellular signals transduction neuroscience

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Ganglioside GQ1b is a tetrasialoganglioside that contains two sialic acid residues linked to an inner galactose unit. It stimulates phosphorylation of several ecto-type protein kinase substrates on the surface of GOTO human neuroblastoma cells when used at a concentration of 5 nM.{25486} Ganglioside GQ1b promotes differentiation of murine embryonic stem cells (mESCs) to neuronal precursor and glial cells via activation of the ERK1/2 pathway.{25483} It also induces differentiation of murine keratinocytes through phosphoinositide turnover.{25487} Ganglioside GQ1b mixture contains ganglioside GQ1b molecular species with C18:1 and C20:1 sphingoid backbones. [Matreya, LLC.]

Size	500 µg
Shipping	dry ice
CAS Number	68652-37-9
Molecular Formula	C₁₀₆H₁₇₈N₆O₅₅ • 4Na (for stearoyl)
SMILES	CCCCCCCCCCCCC/C=C/[C@]([H])([C@](NC(CCCCCCCCCCCCCCCCC)=O)([H])CO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O[C@@H]2O[C@@H]([C@@H]([C@@H]([C@H]2O)O[C@@]3(C([O-])=O)O[C@H]([C@@H]([C@H](C3)O)NC(C)=O)[C@@H](O)[C@H](O[C@@]4(C([O-])=O)O[C@H]([C@@H]([C@H](C4)O)NC(C)=
Molecular Weight	2416,6
Formulation	A lyophilized solid
Purity	≥98%
Custom Code	2922.19
UNSPSC code	12352100

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

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Ganglioside GQ1b Mixture (sodium salt)