Asialo Ganglioside GM1

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Asialo Ganglioside G_M1

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Cat No: 15586

Biochemicals - Lipids

Ganglioside GM1 asialo is a component of cellular lipid rafts and can be formed by the cleavage of the sialic acid residue from ganglioside GM1 (Item No. 19579) by neuraminidase.{25489,37774} Ganglioside GM1 asialo is a glycolipid receptor for P. aeru...

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Correlated keywords:

53124-?73-?5 82197-?20-?4 120528-?30-?5 212699-?20-?2 asialoGM1 ASGM1 lipids ceramide gangliosides glycosphingolipids sialic acids oligosaccharides microdomains rafts neuraminidase bacterial host response signals transduction immune responses residues neuraminidase natural killer T T-cells Tcells signaling immunology asialoganglioside GT1b GA1 Gg4Cer

Product Overview:
Ganglioside GM1 asialo is a component of cellular lipid rafts and can be formed by the cleavage of the sialic acid residue from ganglioside GM1 (Item No. 19579) by neuraminidase.{25489,37774} Ganglioside GM1 asialo is a glycolipid receptor for P. aeruginosa flagellin and stimulates defensive responses in host cells, including extracellular ATP release, calcium mobilization, and ERK1/2 phosphorylation when stimulated by flagellin and an anti-ganglioside GM1 asialo antibody.{25488} The percentage of ganglioside GM1 asialo-positive natural killer (NK) and CD8+ T cells in lung is increased in a mouse model of respiratory syncytial virus (RSV) infection compared with healthy animals.{25489} Depletion of ganglioside GM1 asialo-positive NK and T cells reduces IFN-γ levels in the lung, reduces weight loss, and increases lung viral load in RSV-infected mice. Ganglioside GM1 asialo mixture contains ganglioside GM1 asialo molecular species with C18:1 and C20:1 sphingoid backbones. [Matreya, LLC. Catalog No. 1064]

Size	500 µg
Shipping	dry ice
CAS Number	71012-19-6
Molecular Formula	C₆₂H₁₁₄N₂O₂₃ (for stearoyl)
SMILES	[H][C@](CO[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O[C@@H]3O[C@@H]([C@@H]([C@@H]([C@H]3NC(C)=O)O[C@H]4[C@@H]([C@H]([C@H]([C@H](O4)CO)O)O)O)O)CO)O)O)CO)([C@](O)(/C=C/CCCCCCCCCCCCC)[H])NC(CCCCCCCCCCCCCCCCC)=O
Formulation	A lyophilized powder
Purity	≥98%
Custom Code	2907.29
UNSPSC code	12352100

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

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