Confirm delete?

Bertin Bioreagent
logo
All categories
Contact Us
You are here :

Cimetidine

  • Zoom
    Cimetidine
  • Cimetidine
Cat No: 18743
Biochemicals - Receptor Pharmacology
Cayman
€37.00
Price is excluding VAT and does not include packaging neither shipping

Cimetidine is a histamine H2 receptor antagonist (Ki = 0.6 μM).{30325} It also acts as an inverse agonist, inhibiting basal cAMP production in CHO cells expressing recombinant H2 receptors (IC50 = 1.2 μM). Cimetidine inhibits histamine-induced acid se...

More

This product can only be bought through Cayman Chemical. Please contact us.

- +
Territorial Availability: Available through Bertin Technologies only in Europe
Synonyms:
  • N-cyano-N''-methyl-N'-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]-guanidine
Correlated keywords:
  • 79347-40-3 Acibilin Acinil Biomet Cimal Cimetag Cimetum Dyspamet Edalene Eureceptor Fremet Gastromet Histodil NSC335308 Peptol SKF92334 Tagamet Tamagret Tametin Tratul Ulcedin Ulcedine Ulcerex Ulcerfen Ulcimet Ulcofalk Ulcomedina Ulcomet Ulhys H2 AMP CMT 93
Product Overview:
Cimetidine is a histamine H2 receptor antagonist (Ki = 0.6 μM).{30325} It also acts as an inverse agonist, inhibiting basal cAMP production in CHO cells expressing recombinant H2 receptors (IC50 = 1.2 μM). Cimetidine inhibits histamine-induced acid secretion from isolated bullfrog gastric mucosa (IC50 = 16 μM).{30545} In vivo, it inhibits histamine-induced gastric acid secretion in gastric fistulae and Heidenhain pouches in dogs (ED50 = 1.88 μmol/kg, p.o.). Cimetidine (20 mg/kg per day) also reduces tumor growth and neovascularization in a CMT93 colon cancer mouse syngeneic model.{47643}
Size 5 g
Shipping dry ice
Stability Store at -20 degrees; shelf life 730 days
CAS Number 51481-61-9
Molecular Formula C10H16N6S
SMILES CN/C(NC#N)=N\CCSCC1=C(C)NC=N1
Molecular Weight 252,3
Formulation A crystalline solid
Purity ≥98%
Custom Code 2933.29
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

/ We also advise you

Cross selling for this product : Cimetidine There are 7 products.

Search