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  • Famotidine
Cat No: 23828
Biochemicals - Receptor Pharmacology

Famotidine is a histamine H2 receptor antagonist with a Ki value of 12 nM in fractionated guinea pig cerebral cortex membranes.{36463} It is selective for H2 over H1 and muscarinic receptors (Kis = 4 and 28 µM, respectively, in bovine cerebral cortex)...


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Territorial Availability: Available through Bertin Technologies only in France
  • 3-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)-propanimidamide
Correlated keywords:
  • 214692-67-8 YM11170 H-2 1 antiinflammatory Agufam Amfamox Antodine Apo Apogastine Bestidine Brolin Cepal Dibrit 40 Digervin Dispromil Dispronil Durater Facid Fadin Fadine Fadyn Fagastine FamoABZ Famocid Famodar Famodil Famodin Famodine Famogard Famogast Famolta Famonerton Famopsin Famos Famosan Famoser Famostagine-D Famotal Famotep Famotin Famotine Famowal Famox Famoxal Fanosin Fanox Farmotex Fenox Fibonel Fudone Fuweidin Ganor mite Gaster Gastridin Gastrion Gastro Gastrodomina Gastropen H 2 Bloc Ifada Kemofam Lecedil Logos MK 208 MK208 Mabo Mosul Motiax Muclox Nevofam Nulcerin Panalba Pepcid AC PM Pepcidin Pepcidin Rapitab Pepcidina Pepcidine Pepdif Pepdine Pepfamin Peptan Peptec Peptifam Pepzan Purifam Quamatel Quamtel Restadin Rogasti Sedanium R Servipep Supertidine Tamin Topcid Ulcatif Ulcedine Ulceran Ulcetrax Ulcidine Ulcofam Ulfagel Ulfam Ulfamid Ulfinol Ulped AR Weimok nonsteroidal famo pepdul
Product Overview:
Famotidine is a histamine H2 receptor antagonist with a Ki value of 12 nM in fractionated guinea pig cerebral cortex membranes.{36463} It is selective for H2 over H1 and muscarinic receptors (Kis = 4 and 28 µM, respectively, in bovine cerebral cortex).{23214} Famotidine inhibits histamine-induced acid secretion in isolated canine parietal cells (IC50 = 0.6 µM).{17620} It also suppresses histamine-induced gastric acid secretion in dogs when administered orally and in anesthetized rats when administered intraduodenally (ID50s = 10 and 400 µg/kg, respectively).{17620} Formulations containing famotidine have been used in the treatment of ulcers, gastroesophageal reflux disease (GERD), and heartburn, as well as to decrease the risk of gastrointestinal toxicity associated with non-steroidal anti-inflammatory drugs (NSAIDs).
Size 1 g
Shipping dry ice
CAS Number 76824-35-6
Molecular Formula C8H15N7O2S3
Molecular Weight 337,5
Formulation A crystalline solid
Purity ≥98%
Custom Code 2935.90
UNSPSC code 12352100

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