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Misoprostol (free acid)-d5

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    Misoprostol (free acid)-<wbr/>d<sub>5</sub>
  • Misoprostol (free acid)-<wbr/>d<sub>5</sub>
Cat No: 10010333
Cayman
€77.00
Price is excluding VAT and does not include packaging neither shipping

An internal standard for the quantification of misoprostol (free acid) by GC- or LC-MS.
Misoprostol (free acid)-d5 contains five deuterium atoms at the 16 methyl, 17, and 17' positions. It is intended for use as an internal standard for the quantificat...

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Territorial Availability: Available through Bertin Technologies only in Europe
Product Overview:
An internal standard for the quantification of misoprostol (free acid) by GC- or LC-MS.
Misoprostol (free acid)-d5 contains five deuterium atoms at the 16 methyl, 17, and 17' positions. It is intended for use as an internal standard for the quantification of misoprostol (free acid) by GC- or LC-mass spectrometry (MS). Misoprostol is a PGE1 analog with agonist activity mediated by EP2, EP3, and EP4 receptors. It has been shown to inhibit the formation of gastric lesions in rats (ED50 = 0.31 µg/kg), inhibit superoxide generation in human neutrophils (EC50 = 0.35 µM), and relax fetal rabbit ductus arteriosus (EC50 = 0.36 nM) in a concentration dependent manner. Misoprostol is commonly used in clinical medicine for the prevention of peptic ulcer disease. It has also been used in conjunction with RU-486 for the oral induction of first trimester abortion. Misoprostol contains a C-1 methyl ester and is readily absorbed and rapidly hydrolyzed in humans to the active free acid.
Size: 50 µg
Shipping: wet ice
Stability: Store at -20 degrees; shelf life 365 days maximum after production
CAS Number: 1337917-44-8
Molecular Formula: C21H31D5O5
SMILES: CCCC([2H])([2H])C(O)(C/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O)C([2H])([2H])[2H]
Molecular Weight: 373.5
Formulation: A solution in methyl acetate
Purity: ≥99% deuterated forms (d1-d5)
Custom Code: 2937500000
UNSPSC code: 12352100
UN Number: UN1231

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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ISO Guide 34:2009

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