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CD25 Monoclonal PE Antibody (Clone 143-13)

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    CD25 Monoclonal PE Antibody (Clone 143-<wbr/>13)
  • CD25 Monoclonal PE Antibody (Clone 143-<wbr/>13)
Cat No: 10339
Cayman
€381.00
Price is excluding VAT and does not include packaging neither shipping

Host: Mouse, clone 143-13 • Applications: (+) FC, ICC, and IHC (frozen sections); (−) WB • Species reactivity: (+) Human CD25
Interleukin-2 (IL-2) elicits its effects by binding to a multi-subunit cell-surface receptor that is inducible by various mito...

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: 1 ea

This product can only be bought through Cayman Chemical. Please contact us.

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Territorial Availability: Available through Bertin Technologies only in Europe
Product Overview:
Host: Mouse, clone 143-13 • Applications: (+) FC, ICC, and IHC (frozen sections); (−) WB • Species reactivity: (+) Human CD25
Interleukin-2 (IL-2) elicits its effects by binding to a multi-subunit cell-surface receptor that is inducible by various mitogens. The highest affinity for IL-2 is achieved when all 3 subunits (IL-2Rα or CD25, IL-2Rβ or CD122, and IL-2Rγ or CD132) are expressed together forming a heterotrimeric complex . CD25 is inducible in T-cells by antigen, mitogen or antibodies bound to the T-cell receptor CD3. Binding of IL-2 to IL-2R on NK cells results in their conversion to LAK cells, which release several other cytokines (TNF, INF-γ, and GM-CSF). Activated T-cells will respond to IL-2 by proliferating and secreting cytokines and cytolytic molecules. Activated B cells will proliferate and secrete antibodies.
Size: 1 ea
Shipping: wet ice
Stability: Store at 4 degrees; shelf life 365 days maximum after production
Host: mouse
Clone: 143-13
Application(s):

(+) FC, ICC, and IHC (frozen sections); (−) WB

Specificity:
Formulation: 100 µg of affinity purified, PE labeled monoclonal antibody
Custom Code: 3822000002
UNSPSC code: 12352203

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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