Valrocemide

Valrocemide

CAT N°: 30909
Price:

From 92.00 78.20

Valrocemide is an anticonvulsant and a derivative of valproic acid (Item No. 13033).{52702} In vivo, valrocemide protects against seizures induced by maximal electroshock (MES), pentylenetetrazole (PTZ; Item No. 18682), picrotoxin (Item No. 20771), or bicuculline (Item No. 11727) in mice (ED50s = 151, 132, 275, and 248 mg/kg, respectively). It prevents sound-induced seizures in Frings audiogenic-sensitive mice (ED50 = 52 mg/kg) and MES-induced seizures in rats (ED50 = 73 mg/kg). Valrocemide also prevents seizures in corneally kindled rats (ED50 = 161 mg/kg).

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