sPLA2 (human, recombinant type IIA)
sPLA2 (human, recombinant type IIA)
Secretory phospholipase A2 (sPLA2) (Type IIA) is a calcium-dependent PLA2 superfamily member that is encoded by PLA2G2A in humans.{56210} It...
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Tazarotenic acid is an active metabolite of the retinoid prodrug tazarotene (Item No. 23559), an acetylenic retinoid prodrug that induces epidermal hyperplasia with an ED50 value of 100 nM.{33614,27013} Tazarotenic acid selectively binds retinoic acid receptors (RAR-? and RAR-?) in vitro.{33614} It has a relatively short elimination half-life of one to two hours and is metabolized by cytochrome P450 (CYP) isoforms CYP2C8, CYP26A1, and CYP26B1.{33614,33615}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 10 mg, 25 mg, 5 mg, 50 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 118292-41-4 |
| Molecular formula | C19H17NO2S |
| Smiles | OC(C1=CC=C(C#CC2=CC(C(C)(C)CCS3)=C3C=C2)N=C1)=O |
| Molecular weight | 323,4 |
| Custom code | 2933.39 |
| Formulation | A crystalline solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
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