SR 16584

SR 16584

CAT N°: 10683
Price:

49.00 41.65

Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels in the central and peripheral nervous system. SR 16584 is an antagonist of the ?3?4 nAChR subtype (IC50 = 10.2 ?M).{18814} It shows selective binding of the ?3?4 subtype compared to the ?4?2 and ?7 subtypes (Ki values of 0.508, >100, and >100 ?M, respectively), indicating that it should be a useful tool for receptor subtype studies.{18814}

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