SHS4121705

SHS4121705

CAT N°: 31053
Price:

From 176.00 149.60

SHS4121705 is an orally bioavailable mitochondrial uncoupler.{54188} It increases oxygen consumption rate in L6 rat myoblast cells with an EC50 value of 4.3 ?M. SHS4121705 (25 mg/kg per day in the diet) reduces hepatic steatosis, liver triglyceride levels, and plasma alanine aminotransferase (ALT) levels in Stelic animal model (STAM) mice, a model of non-alcoholic steatohepatitis (NASH).

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