Saikosaponin B<sub>1</sub>

Saikosaponin B1

CAT N°: 34609
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Saikosaponin B1 is a triterpenoid saponin that has been found in B. chinense and has diverse biological activities.{62388,62334,62389} It is an agonist of the serotonin (5-HT) receptor subtype 5-HT2C (EC50 = 147.41 µM in HEK293 cells expressing the human receptor in a calcium mobilization assay).{62388} Saikosaponin B1 (100 µg/ml) stimulates prostaglandin E2 (PGE2; Item No. 14010) production in isolated rat peritoneal macrophages.{62334} It protects SH-SY5Y cells from hydrogen peroxide-induced cell death when used at a concentration of 50 µg/ml.{62389}

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