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RHC-80267 is an inhibitor of diacylglycerol lipase (DAGL; IC50 = 4 µM for the canine platelet enzyme).{27089} It also inhibits the serine hydrolases KIAA1363, fatty acid amide hydrolase (FAAH), BAT5, phospholipase A2 (PLA2), hormone-sensitive lipase (HSL), and acetylcholinesterase (AChE) by greater than 60% when used at a concentration of 50 µM.{16688} RHC-80267 (0.1-10 µM) potentiates ACh-induced relaxation of isolated rat mesenteric arteries.{58483}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 10 mg, 25 mg, 5 mg, 50 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 83654-05-1 |
| Smiles | O=C(NCCCCCCNC(O/N=C1CCCCC/1)=O)O/N=C2CCCCC2, O=C(NCCCCCCNC(O/N=C1CCCCC/1)=O)O/N=C2CCCCC2, O=C(NCCCCCCNC(O/N=C1CCCCC/1)=O)O/N=C2CCCCC2, O=C(NCCCCCCNC(O/N=C1CCCCC/1)=O)O/N=C2CCCCC2 |
| Molecular weight | 394,5 |
| Custom code | 2922.19 |
| Formulation | A crystalline solid |
| Purity | ≥95% |
| UNSPSC code | 12352100 |
Cayman Chemical’s mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.
Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
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