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BAY-K-8644, originally described as a modulator of potential operated calcium channels, exists as two enantiomers that have opposite actions.{24672,24674,24673} (R)-(+)-BAY-K-8644 is an L-type channel blocker that has negative inotropic and vasodilatory effects at 1 ?M.{24675,24676,24673} Intracerebroventricular administration of this enantiomer has no effect on motor function in mice, whereas (S)-(?)-BAY-K-8644 impairs rotarod and motor activity, an effect that is blocked by (R)-(+)-BAY-K-8644.{24674}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 mg, 10 mg, 5 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 98791-67-4 |
| Molecular formula | C16H15F3N2O4 |
| Smiles | O=C(OC)C1=C(C)NC(C)=C([N+]([O-])=O)[C@@H]1C2=CC=CC=C2C(F)(F)F |
| Molecular weight | 356,3 |
| Custom code | 2933.39 |
| Formulation | A crystalline solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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