Propantheline (bromide)

Propantheline (bromide)

CAT N°: 23609
Price:

From 39.00 33.15

Propantheline is an anticholinergic agent.{41353,41354,41355} It inhibits contraction of isolated guinea pig ileum induced by acetylcholine (Item No. 23829) and reduces intensity of vagal-stimulated gastric contractions in rats.{41353} Propantheline (5 mg/kg, s.c.) increases gastric pH and prevents pyloric ligature-induced gastric ulcer formation in Shay rats.{41354} It also inhibits basal and pentagastrin-, but not histamine-, stimulated gastric secretion in a rhesus monkey model of chronic gastric fistula.{41355} Formulations containing propantheline have been used to treat stomach and intestinal spasms associated with irritable bowel syndrome.

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