Hydroflumethiazide

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Hydroflumethiazide

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Cat No: 23612

Biochemicals - Small Molecule Inhibitors

Hydroflumethiazide is a thiazide diuretic that also inhibits carbonic anhydrase (CA).{23242} It is selective for CAII, VB, VII, IX, XII, and XIV (Kis = 305-235 nM) over CAI, IV, and VI (Kis = 2,840-8,250 nM) and CAIII, VA, and XIII (Kis = >10 µM). Diu...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

3,4-dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide, 1,1-dioxide

Correlated keywords:

bristab bristurin di-ademil diademil diucardin diumide K diuredemina diurometon elodrine finuret flutizide glomerulin hidroalogen hydol hydrenox leodrine metflorylthiazidine methforylthiazidine NSC44627 NaClex glaxo olmagran rodiuran rontyl saluron salutensin sisuril trifluoromethylhydrothiazide vergonil Hidroflumetiazid Spandiuril Dihydroflumethiazide CA-II III I

Product Overview:
Hydroflumethiazide is a thiazide diuretic that also inhibits carbonic anhydrase (CA).{23242} It is selective for CAII, VB, VII, IX, XII, and XIV (Kis = 305-235 nM) over CAI, IV, and VI (Kis = 2,840-8,250 nM) and CAIII, VA, and XIII (Kis = >10 µM). Diuretics of the thiazide class, of which hydroflumethiazide is a member, inhibit the renal Na+/Cl- cotransporter.{37204} Formulations containing hydroflumethiazide have been used as diuretics.

Size	50 mg
Shipping	wet ice
CAS Number	135-09-1
Molecular Formula	C₈H₈F₃N₃O₄S₂
SMILES	O=S1(C2=C(C=C(C(F)(F)F)C(S(N)(=O)=O)=C2)NCN1)=O
Molecular Weight	331,3
Formulation	A solid
Purity	≥98%
Custom Code	2935.90
UNSPSC code	12352100

Technical File

MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.