(+)-Borneol

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(+)-Borneol

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Cat No: 23467

Biochemicals - Ion Channel Modulation

(+)-Borneol is a bicyclic monoterpene and a stereoisomer of (–)-borneol (Item No. 23468) that has been found in various plants, including S. tomentosa, and has diverse biological activities including analgesic, neuroprotective, antioxidant, and antimi...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

(1R,2S,4R)-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-ol

Correlated keywords:

salvia anti-oxidant microbial ?-1 ?-2 ?-2 gaba-a SHSY5Y A?-42 Escherichia Staphylococcus Pseudomonas Proteus Salmonella neuro-protective

Product Overview:
(+)-Borneol is a bicyclic monoterpene and a stereoisomer of (–)-borneol (Item No. 23468) that has been found in various plants, including S. tomentosa, and has diverse biological activities including analgesic, neuroprotective, antioxidant, and antimicrobial properties.{36773,36860,36861,36862} (+)-Borneol is a positive allosteric modulator of α1β2γ2L subunit-containing GABAA receptors (EC50 = 248 μM for human recombinant receptors).{36773} It dose-dependently increases the paw withdrawal threshold following segmental spinal nerve ligation surgery or intraplantar injection of complete Freund's adjuvant (CFA) in mouse paw.{36860} (+)-Borneol (100 μM) inhibits increases in reactive oxygen species (ROS) levels and cytotoxicity in SH-SY5Y neuroblastoma cells incubated with amyloid-β (1-42) (Aβ42; Item No. 20574).{36861} It also inhibits the growth of Gram-positive and Gram-negative bacteria in vitro, including E. coli, S. aureus, P. aeruginosa, P. vulgaris, and S. typhimurium (MICs = 125-250 μg/mL).{36862} Formulations containing (+)-borneol have been used as fragrance ingredients.

Size	500 mg
Shipping	dry ice
CAS Number	464-43-7
Molecular Formula	C₁₀H₁₈O
SMILES	C[C@]1(C2(C)C)CC[C@@H]2C[C@@H]1O
Molecular Weight	154,3
Formulation	A crystalline solid
Purity	≥95%
Custom Code	2902.90
UNSPSC code	12352100

Technical File

MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.