(±)-Camphene

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(±)-Camphene

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Cat No: 24478

Biochemicals - Natural Products

(±)-Camphene is a bicyclic monoterpene found in a variety of plants, including Cannabis, that has diverse biological activities, including antiproliferative, pro-apoptotic, hypolipidemic, and insecticidal properties.{42303,47119,47120,47121,47122} It ...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

2,2-dimethyl-3-methylene-bicyclo[2.2.1]heptane

Correlated keywords:

565-00-4 anti-proliferative proapoptotic B16F10 F10Nex2 A 2058 HL60 U87 MG SKBR3 WR1339 Helicoverpa YS methylenenorcamphane B-16 F-10 Nex-2 NSC4165

Product Overview:
(±)-Camphene is a bicyclic monoterpene found in a variety of plants, including Cannabis, that has diverse biological activities, including antiproliferative, pro-apoptotic, hypolipidemic, and insecticidal properties.{42303,47119,47120,47121,47122} It inhibits proliferation of B16/F10-Nex2 mouse melanoma, as well as human A2058 melanoma, HL-60 leukemia, U87MG glioblastoma, and SK-BR-3 breast cancer cells (IC50s = 71.2, 35.2, 27, 55.4, and 34.7 μg/ml, respectively).{47119} (±)-Camphene (70 μg/ml) increases caspase-3 activity and induces apoptosis and endoplasmic reticulum stress in B16/F10-Nex2 cells. It lowers plasma levels of total cholesterol, LDL cholesterol, and triglycerides (TGs) in a Triton WR-1339-induced rat model of hyperlipidemia when administered at a dose of 1.5 μg/g.{47120} Dietary administration of (±)-camphene (0.2%) also inhibits hepatic steatosis and insulin resistance in a mouse model of high-fat diet-induced obesity.{47121} It also has larvicidal activity against third instar H. armigera larvae (LC50 = 10.64 μg/ml) and ovicidal activity against H. armigera eggs (EC50 = 35.39 μg/ml).{47122} Formulations containing (±)-camphene have been used as perfume and food additives.

Size	100 mg
Shipping	dry ice
CAS Number	79-92-5
Molecular Formula	C₁₀H₁₆
SMILES	C=C1C2CCC(C2)C1(C)C
Molecular Weight	136,2
Formulation	A solid
Purity	≥97%
Custom Code	2902.90
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.