(+)-Valencene

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(+)-Valencene

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Cat No: 23167

Biochemicals - Natural Products

(+)-Valencene is a sesquiterpene that has been found in C. sativa and is an aromatic component of orange essence oil.{43235,43243} (+)-Valencene (50 µM) induces heme oxgenase-1 (HO-1) expression in macrophages and inhibits the expression of inducible ...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

(1R,7R,8aS)-1,2,3,5,6,7,8,8a-octahydro-1,8a-dimethyl-7-(1-methylethenyl)-naphthalene

Correlated keywords:

20479-02-1 Valencen cannabis HMGB-1 HO1 NSC148969 HO1 HMGB-1 RAW264.7 lipopolysaccharide

Product Overview:
(+)-Valencene is a sesquiterpene that has been found in C. sativa and is an aromatic component of orange essence oil.{43235,43243} (+)-Valencene (50 µM) induces heme oxgenase-1 (HO-1) expression in macrophages and inhibits the expression of inducible nitric oxide synthase (iNOS), the production of nitric oxide (NO), and the release of high-mobility group box-1 (HMGB1) in RAW 264.7 cells stimulated with LPS.{43244} It also increases the survival rate in a mouse model of sepsis induced by cecal ligation and puncture. (+)-Valencene has been used in the synthesis of nootkatone (Item No. 24910).{43245}

Size	1 g
Shipping	wet ice
CAS Number	03/07/4630 00:00
Molecular Formula	C₁₅H₂₄
SMILES	CC([C@@H]1CCC2=CCC[C@@H](C)[C@]2(C)C1)=C
Molecular Weight	204,4
Formulation	A liquid
Purity	≥75%
Custom Code	3822.19
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.