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Hsc70 (human, recombinant)

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    Hsc70 (human, recombinant)
  • Hsc70 (human, recombinant)
Cat No: 22737
Proteins - Enzymes
Cayman

Hsc70 is a chaperone from the Hsp70 chaperone family encoded by the HspA8 gene that shares 85% sequence identity to Hsp70 (encoded by HspA1A gene), and is one of the constitutively expressed members from this family.{36100} Hsc70 acts as the main hous...

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: 50 µg

This product can only be bought through Cayman Chemical. Please contact us.

Territorial Availability: Available through Bertin Technologies only in France
Correlated keywords:
  • Hsp-70 A1A A8 74 Hsc-70 54 71 73 A10 A8 LAP-1 NIP-71 constitutive heat shock protein EC 3.6.3.51 EC3.6.3.51 hsc54 hsc71 hsc73 hsp71 hsp74 hspa10 lap1 lipopolysaccharide-associated NIP71 escherichia
Product Overview:
Hsc70 is a chaperone from the Hsp70 chaperone family encoded by the HspA8 gene that shares 85% sequence identity to Hsp70 (encoded by HspA1A gene), and is one of the constitutively expressed members from this family.{36100} Hsc70 acts as the main housekeeping protein but is also involved in many functions such as ubiquitin-proteasome degradation pathway and transporting cytoplasmic proteins into the nucleus.{36101,36102} Hsc70 also garnered interests as a potential therapeutic target since promoting accumulation of unfolded proteins can serve as a potential strategy to cause tumor death.{19631}
Size 50 µg
Shipping dry ice
Formulation 50 mM HEPES, pH 8.0, and 150 mM sodium chloride
Purity ≥90% estimated by SDS-PAGE
Custom Code 3504.00
UNSPSC code 12352204

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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