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Trofosfamide

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    Trofosfamide
  • Trofosfamide
Cat No: 21874
Biochemicals - Dna Alkylating Agents
Cayman

Trofosfamide is a nitrogen mustard alkylating agent and a derivative of cyclophosphamide (Item No. 13849) that has antiproliferative activities.{52010,52011} It increases the number of micronucleated polychromatic red blood cells isolated from mouse b...

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Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • N,N,3-tris(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine, 2-oxide
Correlated keywords:
  • 39471-04-0 63228-86-4 Asta Z-4828 Z4828 AstaZ4828 Ixoten NSC109723 Trifosfamide Trilofosfamida Trilophosphamide Triphosphamide Trisfosfamide Trofosfamid Trophosphamid Trophosphamide Z 4828 Ixoten Genoxal Trofosfamida NSC26271 NSC-26271 Cyclophosphamide Antineoplastic anti-proliferative micro-nucleated poly-chromatic cyclo
Product Overview:
Trofosfamide is a nitrogen mustard alkylating agent and a derivative of cyclophosphamide (Item No. 13849) that has antiproliferative activities.{52010,52011} It increases the number of micronucleated polychromatic red blood cells isolated from mouse bone marrow, indicating cytogenetic activity, when administered at doses of 40, 80, and 160 mg/kg.{52009} Trofosfamide (100 mg/kg) inhibits proliferation of isolated splenocytes in the allogenic mixed lymphocyte reaction.{52010} It reduces sheep red blood cell-induced increases in the number of antibody-producing spleen cells isolated from rats when administered at a dose of 40 mg/kg.{52011}
Size 5 mg
Shipping dry ice
CAS Number 22089-22-1
Molecular Formula C9H18Cl3N2O2P
SMILES ClCCN(CCCl)P1(OCCCN1CCCl)=O
Molecular Weight 323,6
Formulation A crystalline solid
Purity ≥95%
Custom Code 2921.29
UNSPSC code 12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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Cross selling for this product : Trofosfamide There are 2 products.

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