4-deoxy Pyridoxine (hydrochlorid

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4-deoxy Pyridoxine (hydrochloride)

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Cat No: 21863

Biochemicals - Small Molecule Inhibitors

4-deoxy Pyridoxine (DOP) is a vitamin B6 antimetabolite with diverse biological activities.{38612,38613,38614,38615,38616} It inhibits transport of pyridoxine (Item No. 20706), pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cel...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

5-hydroxy-4,6-dimethyl-3-pyridinemethanol, monohydrochloride

Correlated keywords:

61-67-6 Deoxypyridoxol Desoxyadermin Desoxypyridoxine 4DPD anti-metabolite Saccharomyces MLE12 IL6 TNF? Trichinella

Product Overview:
4-deoxy Pyridoxine (DOP) is a vitamin B6 antimetabolite with diverse biological activities.{38612,38613,38614,38615,38616} It inhibits transport of pyridoxine (Item No. 20706), pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells.{38612} DOP inhibits sphingosine-1-phosphate (S1P) lyase and reduces cyclic stretch-induced apoptosis in alveolar epithelial MLE-12 cells.{38613} DOP (5 mg, i.p.) reduces lysyl oxidase activity by 26% and reduces collagen and elastin crosslinking, resulting in limb abnormalities in chick embryos.{38614} It decreases latency to first seizure in mice (ED50 = 1 mmol/kg) and increases the occurrence and duration of myoclonic responses in baboons with photosensitive epilepsy.{38615} DOP reduces TNF-α and IL-6 production in mice infected with T. spiralis.{38616}

Size	100 mg
Shipping	dry ice
CAS Number	148-51-6
Molecular Formula	C₈H₁₁NO₂ • HCl
SMILES	OCC1=C(C)C(O)=C(C)N=C1.Cl
Molecular Weight	189,6
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2933.39
UNSPSC code	12352100

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MSDS

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

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