L-(?)-?-Methyldopa

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L-(?)-?-Methyldopa

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Cat No: 21814

Biochemicals - Receptor Pharmacology

L-(−)-α-Methyldopa is a dopamine (DOPA) decarboxylase inhibitor (ED50 = 21.8 mg/kg) and has antihypertensive activity in vitro and in vivo.{36001,36002,36000} L-(−)-α-Methyldopa enters the CNS and is metabolized to form α-methylnorepinephrine which ac...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

3-hydroxy-?-methyl-L-tyrosine

Correlated keywords:

779-08-8 1339-75-9 4290-08-8 88620-56-8 133161-54-3 MD a-methyldopa a2 NSC169916 MK351 anti-hypertensive central nervouse system 3,4-dihydroxyphenylalanine AMD aldochlor aldomet aldometil aldomin aldomine medopa alphamethyldopa 1440L baypresol dopamet dopatec dopegyt elanpres equibar lederopa medomet medopren methoplain Nr.C 2294 presinol presolisin sembrina (S)-

Product Overview:
L-(−)-α-Methyldopa is a dopamine (DOPA) decarboxylase inhibitor (ED50 = 21.8 mg/kg) and has antihypertensive activity in vitro and in vivo.{36001,36002,36000} L-(−)-α-Methyldopa enters the CNS and is metabolized to form α-methylnorepinephrine which acts as an agonist at α2-adrenergic receptors.{36001,36000} Formulations containing L-(−)-α-methyldopa are used to lower blood pressure.{36002} L-(−)-α-Methyldopa also improves trophoblast and endothelial cellular interactions in vitro.{36001}

Size	5 g
Shipping	room temp.
CAS Number	555-30-6
Molecular Formula	C₁₀H₁₃NO₄
SMILES	OC1=C(O)C=CC(C[C@](C)(N)C(O)=O)=C1
Molecular Weight	211,2
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2918.99
UNSPSC code	12352100

Technical File

MSDS

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

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