Nitrofurazone

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Nitrofurazone

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Cat No: 21656

Nitrofurazone is a nitrofuran antibiotic that is active against a variety of Gram-negative and Gram-positive bacteria including laboratory strains of S. aureus, E. faecalis, and E. coli (MICs = 8 μg/ml for all) as well as clinical isolates of several ...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

2-[(5-nitro-2-furanyl)methylene]-hydrazinecarboxamide

Correlated keywords:

8027-71-2 60051-85-6 furacin Aldomycin Alfucin Amifur Babrocid Chemofuran Coxistat Fura-Septin FuraZin Furacilin Furacilinum Furacine; Furacinetten Furacoccid Furacycline Furalcyn Furaldon Furaplast Furaseen Furaskin Furaziline Furazol W Furesol Mammex Mastofuran Monafuracin NFS NSC1602 NSC2100 NSC44009 Nefco Nfz mix Nifucin Nifuzon Nitrofural Nitrofuraldehyde semicarbazone Nitrozone Otofural Topifuran Vabrocid Veterinary nitrofurazone Staphylococcus Enterococcus Escherichia Proteus anti-biotic

Product Overview:
Nitrofurazone is a nitrofuran antibiotic that is active against a variety of Gram-negative and Gram-positive bacteria including laboratory strains of S. aureus, E. faecalis, and E. coli (MICs = 8 μg/ml for all) as well as clinical isolates of several urinary tract pathogens including Enterococcus, coagulase-negative staphylococci, Klebsiella, and P. mirabilis (MICs = 2-64 μg/ml).{37741,37742} Nitrofurazone induces mutagenicity in mammalian and bacterial cell-based assays and carcinogenesis, reproductive effects, and toxicity in rats and mice (LD50s = 590 and 640 mg/kg, respectively).{37743} Formulations containing nitrofurazone have been used in the topical treatment and prevention of bacterial infections in humans and animals as well as oral treatment of trypanosomiasis.

Size	25 g
Shipping	dry ice
CAS Number	59-87-0
Molecular Formula	C₆H₆N₄O₄
SMILES	NC(N/N=C/C1=CC=C([N+]([O-])=O)O1)=O
Molecular Weight	198,1
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2932.19
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.