Confirm delete?

Bertin Bioreagent
logo
All categories
Contact Us
You are here :

Cicaprost

  • Zoom
    Cicaprost
  • Cicaprost
Cat No: 16831
Biochemicals - Eicosanoids
Cayman
€242.00
Price is excluding VAT and does not include packaging neither shipping

Prostaglandin I2 (PGI2, prostacyclin) is the most potent endogenous vasodilator that affects both the systemic and pulmonary circulation.{643} Cicaprost is a PGI2 analog that is orally active with prolonged availability in vivo, having a terminal half ...

More

This product can only be bought through Cayman Chemical. Please contact us.

- +
Territorial Availability: Available through Bertin Technologies only in Europe
Synonyms:
  • 2-[2-[(2E,3aS,4S,5R,6aS)-hexahydro-5-hydroxy-4-[(3S,4S)-3-hydroxy-4-methyl-1,6-nonadiyn-1-yl]-2(1H)-pentalenylidene]ethoxy]-acetic acid
Correlated keywords:
  • Prostaglandin I2 PGI2 prostacyclins vasodilators cardiovascular diseases inflammation mitogenesis cancers orally active inflammatory Epoprostenol Sodium(5Z,9alpha,11alpha,13E,15S)-Isomer Epoprostenol Sodium Prostaglandin I(2) Prostaglandin I2 Prostacyclin Epoprostenol Epoprostanol Flolan PGI2 PGX
Product Overview:
Prostaglandin I2 (PGI2, prostacyclin) is the most potent endogenous vasodilator that affects both the systemic and pulmonary circulation.{643} Cicaprost is a PGI2 analog that is orally active with prolonged availability in vivo, having a terminal half life in plasma of one hour.{6640}{18554} In addition to their effects on smooth muscle, PGI2 analogs, including cicaprost, have been shown to inhibit the pro-inflammatory actions of certain leukocytes, suppress cardiac fibrosis, and block mitogenesis of certain cell types.{18547}{18548}{18546} Importantly, cicaprost has been shown to strongly reduce lung and lymph node metastasis in rats, suggesting that it might be useful in cancer therapy.{19177}
Size 500 µg
Shipping dry ice
Stability Store at -20 degrees; shelf life 365 days
CAS Number 94079-80-8
Molecular Formula C22H30O5
SMILES O[C@@H]1C[C@H](C/2)[C@H](CC2=C\COCC(O)=O)[C@H]1C#C[C@@H](O)[C@@H](C)CC#CCC
Molecular Weight 374,5
Formulation A solution in methyl acetate
Purity ≥98%
Custom Code 2937.50
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

/ We also advise you

Cross selling for this product : Cicaprost There are 10 products.

Search