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GLYX 13

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    GLYX 13
  • GLYX 13
Cat No: 21385
Biochemicals - Ion Channel Modulation
Cayman

GLYX 13 is a monoclonal antibody-derived tetrapeptide that acts as a partial agonist at the glycine site of the N-methyl-D-aspartate (NMDA) receptor.{33821,33823} It is active in vivo when administered intravenously, and it readily passes through the ...

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Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • L-threonyl-L-prolyl-L-prolyl-L-threoninamide
Correlated keywords:
  • GLYX13 Thr-Pro NH2 anti-depressant TPPT aspartic BBB BV-102 BV102
Product Overview:
GLYX 13 is a monoclonal antibody-derived tetrapeptide that acts as a partial agonist at the glycine site of the N-methyl-D-aspartate (NMDA) receptor.{33821,33823} It is active in vivo when administered intravenously, and it readily passes through the blood-brain barrier.{33821,33818} GLYX 13 has diverse effects in animals, as it blocks neuropathic pain, enhances learning and memory, and significantly reduces anxiety.{33823,33818,33820} GLYX 13 induces rapid antidepressant-like effects in animal models and rescued normal behavior in a rat model of autism.{33819,33822,33824}
Size 1 mg
Shipping dry ice
CAS Number 117928-94-6
Molecular Formula C18H31N5O6
SMILES O=C([C@@H](N)[C@H](O)C)N1[C@H](C(N2[C@H](C(N[C@H](C(N)=O)[C@H](O)C)=O)CCC2)=O)CCC1
Molecular Weight 413,5
Formulation A crystalline solid
Purity ≥98%
Custom Code 2922.19
UNSPSC code 12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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Cross selling for this product : GLYX 13 There are 3 products.

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