Confirm delete?

Bertin Bioreagent
logo
All categories
Contact Us
You are here :

N-Desmethylclobazam (CRM)

  • Zoom
    N-Desmethylclobazam (CRM)
  • N-Desmethylclobazam (CRM)
Cat No: 18888
Biochemicals - Analytical Standards
Cayman

N-Desmethylclobazam (CRM) (Item No. 18888) is a certified reference material that is structurally categorized as a benzodiazepine. It is a major active metabolite of clobazam, produced primarily by the action of cytochrome P450 isoform 3A4.{31385} N-D...

More
: 100 µg

This article is not for sale online.
Contact us for more information about this article.

Territorial Availability: Available through Bertin Technologies only in France
Technical Warning: Bertin Technologies restricts the sale of this product to licensed controlled substance laboratories and qualified academic research institutions. Please contact us for further details.
Special Advice: Reference Materials RMs and Certified Reference Materials CRMs are dispatched directly to the end-user in accordance with ISO requirements. Please check regulation status before ordering; additionel fees can apply.
Synonyms:
  • 8-chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione
Correlated keywords:
  • clofazin demethylclobazam desmethylclobazam N-demethylclobazam norclobazam GABAA cytochrome P450 isoform 3A4 CYP3A4 CYP-3A4 CYP4503A4 CYP450-3A4 CYP-4503A4 GABA-A ?-aminobutyric acid g-aminobutyric
Product Overview:
N-Desmethylclobazam (CRM) (Item No. 18888) is a certified reference material that is structurally categorized as a benzodiazepine. It is a major active metabolite of clobazam, produced primarily by the action of cytochrome P450 isoform 3A4.{31385} N-Desmethylclobazam (CRM) positively modulates GABAA receptors (EC50s range from 98 to 151 µM, depending on subunit configuration).{31386} This product is intended for research and forensic applications.
Size 100 µg
Shipping dry ice
CAS Number 22316-55-8
Molecular Formula C15H11ClN2O2
SMILES ClC1=CC(N(C2=CC=CC=C2)C(C3)=O)=C(C=C1)NC3=O
Molecular Weight 286,7
Formulation A 100 µg/ml solution in acetonitrile
Custom Code 3822.90
UNSPSC code 12352100

Click here to ask for your quote and get 15% off Cayman's products.

 

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

/ We also advise you

Cross selling for this product : N-Desmethylclobazam (CRM) There are 8 products.

Search