Vitamin B12 (hydrate)

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Vitamin B₁₂ (hydrate)

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Cat No: 18425

Biochemicals - Natural Products

Vitamin B12 is a water-soluble vitamin with roles in brain and nervous system functioning and blood formation through regulation of DNA synthesis, cellular metabolism, fatty acid metabolism, and amino acid metabolism.{29880} It belongs to the corrinoi...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

5,6-dimethyl-1-(3-O-phosphono-?-D-ribofuranosyl)-1H-benzimidazole monoester with cobinamide cyanide, inner salt, hydrate

Correlated keywords:

68-19-9 8023-26-5 8039-03-0 11037-08-4 24436-34-8 cyano hydroxo methyl-cobalamin Ado Me-B12 Anacobin Antipernicin Apikobal B-Twelve-Ora Bedodeka Bedoz Behepan Berubi Berubigen Betalin Betaline-12 Betolvex Byladoce Castle's extrinsic gastric factor CN-B12 CNB12 Cobalin Cobamin Cobinamide Cotel Covit Cromatonbic-B12 Crystamin Crystamine Cyano-B12 Cyanocobalamin Cyanocobalamine Cycolamin Cykobemin Cykobeminet Cyomin Cyredin Cytacon Cytamen Cytobion Depinar Dicopac Kit Dobetin Docemine Docibin Docigram Docivit Dodecabee Dodecavite Dodex Ducobee Duodecibin Eligen-B12 Embiol Emociclina Eritrone Erycytol Erythrotin Euhaemon Fresmin Hemo-b-doze Hemomin Hepagon Hepavis Hepavit Hepcovite Lactobacillus lactis dorner factor LLD Macrabin Megalovel Milbedoce Millevit Nagravon Nascobal Normocytin NSC 80365 NSC80365 Optovite-B12 Pernaemon Pernaevit Pernipuron Plecyamin Poyamin Rebramin Redamina Redisol Regividerm cream Rheumazin Rhodacryst Rubesol Rubivamine Rubramin Rubramin-PC Rubripca Rubrocitol SMARTShot-B12 Sytobex Vibalt Vibisone Virubra Vita-rubra Vitarubin Vitasprint B12 Vitral

Product Overview:
Vitamin B12 is a water-soluble vitamin with roles in brain and nervous system functioning and blood formation through regulation of DNA synthesis, cellular metabolism, fatty acid metabolism, and amino acid metabolism.{29880} It belongs to the corrinoid group of compounds, which contain a corrin macrocycle, and is produced only by certain bacteria and archaea.{29881} Reference to vitamin B12 usually encompasses a group of cobalt-containing compounds (or cobalamins), which include cyanocobalamin, hydroxocobalamin, 5'-deoxyadenosylcobalamin (AdoB12), and methylcobalamin (MeB12). These forms serve as cofactors in isomerase-, methyltransferase-, and dehalogenase-catalyzed reactions.{29879} For example, methylmalonyl coenzyme A mutase acts on AdoB12 to convert methylmalonyl-CoA to succinyl-CoA, an important step before entry into the Kreb’s cycle. Additionally, methionine synthase uses MeB12 to transfer a methyl group from 5-methyltetrahydrofolate to homocysteine to generate tetrahydrofolate and methionine, which is important for DNA synthesis.{29515}

Size	500 mg
Shipping	dry ice
CAS Number	194937-59-2
Molecular Formula	C₆₃H₈₈CoN₁₄O₁₄P • XH₂O
SMILES	C[C@@]12[N]([Co+3]34([N-]5[C@]2([H])[C@H](CC(N)=O)[C@@](C)(CCC(NC[C@@H](C)O[P]6([O-])=O)=O)C5=C(C)C([C@@H](CCC(N)=O)C7(C)C)=[N]3C7=CC8=[N]4C([C@](CC(N)=O)(C)[C@@H]8CCC(N)=O)=C9C)([N]%10=CN([C@]%11([H])[C@H](O)[C@H](O6)[C@@H](CO)O%11)C%12=CC(C)=C(C)C=C%10%
Molecular Weight	1355,4
Formulation	A crystalline solid
Purity	≥95%
Custom Code	2936.26
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.