5'-deoxy Thymidine

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5'-deoxy Thymidine

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Cat No: 18154

Biochemicals - Anti-Infection

The pyrimidine thymidine consists of thymine combined with deoxyribose. Prior to polymerization into DNA, thymidine must be phosphorylated at the hydroxyl group on carbon 5 of the ribose moiety. 5'-deoxy Thymidine is a form of thymidine in which the hy...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

5'-deoxy-thymidine

Correlated keywords:

biochemical inhibitor nucleotide modified thymidine thymine inhibit 5-deoxy

Product Overview:
The pyrimidine thymidine consists of thymine combined with deoxyribose. Prior to polymerization into DNA, thymidine must be phosphorylated at the hydroxyl group on carbon 5 of the ribose moiety. 5'-deoxy Thymidine is a form of thymidine in which the hydroxyl group on carbon 5 of ribose has been replaced with hydrogen. As a result, this compound cannot be phosphorylated and used by DNA polymerase in the synthesis of DNA. 5'-deoxy Thymidine is readily imported by cellular nucleoside importers and competitively inhibits the influx of thymidine.{29379} It demonstrates antibacterial activity against B. subtilis and S. aureus.{29380}

Size	1 mg
Shipping	dry ice
CAS Number	3458-14-8
Molecular Formula	C₁₀H₁₄N₂O₄
SMILES	CC1=CN(C(NC1=O)=O)[C@H]2C[C@H](O)[C@@H](C)O2
Molecular Weight	226,2
Formulation	A crystalline solid
Purity	≥95%
Custom Code	2933.49
UNSPSC code	12352100

Technical File

MSDS

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

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