Angiotensin Fragment 1-7 (acetat

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Angiotensin Fragment 1-7 (acetate)

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Cat No: 17594

Biochemicals - Receptor Pharmacology

In the renin-angiotensin system, angiotensin I is cleaved by angiotensin-converting enzyme (ACE) to form angiotensin II, which has effects on blood pressure, as well as fluid and electrolyte homeostasis. Angiotensin fragment 1-7 is an angiotensin metab...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

5-L-isoleucine-1-7-angiotensin II

Correlated keywords:

51833-78-4 osmoregularity antidiuretic metabolic syndrome renin-angiotensin system angiotensin angiotensin-converting enzyme ACE angiotensin II metabolite biochemical endocrinology receptor agonist peptide

Product Overview:
In the renin-angiotensin system, angiotensin I is cleaved by angiotensin-converting enzyme (ACE) to form angiotensin II, which has effects on blood pressure, as well as fluid and electrolyte homeostasis. Angiotensin fragment 1-7 is an angiotensin metabolite that functions as a type 1 angiotensin II receptor agonist whereupon it can control hydroelectrolyte balance and demonstrates vasodilatory and anti-inflammatory actions in opposition to various adverse effects of angiotensin II (Item No. 17150).{28801} This peptide can be generated by the action of ACE2, a homolog of ACE, on angiotensin II or by the action of neprilysin on angiotensin I.{24075} It has been studied in the context of ameliorating the symptoms of metabolic syndrome.{28802,28803}

Size	1 mg
Shipping	dry ice
Molecular Formula	C₄₁H₆₂N₁₂O₁₁ • XC₂H₄O₂
SMILES	O=C([C@H](CC1=CNC=N1)NC([C@@]([H])(NC([C@H](CC2=CC=C(C=C2)O)NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)CCCNC(N)=N)=O)C(C)C)=O)=O)[C@H](CC)C)=O)N3CCC[C@H]3C(O)=O.CC(O)=O
Molecular Weight	899
Formulation	A crystalline solid
Purity	≥95%
Custom Code	3504.00
UNSPSC code	12352100

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