(E)-2-Hexadecenal

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(E)-2-Hexadecenal

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Cat No: 17566

Biochemicals - Lipids

Sphingosine-1-phosphate (S1P), a bioactive lipid involved in many signaling processes, is irreversibly degraded by the membrane-bound S1P lyase. (E)-2-Hexadecenal is a sphingolipid degradation product resulting from the action of S1P lyase. It can be f...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

(2E)-2-hexadecenal

Correlated keywords:

3163-37-9 51534-41-9 sphingolipid S1P lyase long chain fatty aldehyde apoptosis DNA cytoskeletal research sphingosine-1-phosphate bioactive lipid signaling 2 E 2E hexadecenoic acid biochemical ceramide damage repair lipid mediator

Product Overview:
Sphingosine-1-phosphate (S1P), a bioactive lipid involved in many signaling processes, is irreversibly degraded by the membrane-bound S1P lyase. (E)-2-Hexadecenal is a sphingolipid degradation product resulting from the action of S1P lyase. It can be further oxidized to (2E)-hexadecenoic acid by long-chain fatty aldehyde dehydrogenase prior to activation via coupling to coenzyme A. (E)-2-Hexadecenal has been shown to induce cytoskeletal reorganization that results in cell rounding, detachment, activation of downstream JNK targets, and eventual apoptosis in various cell types.{28538} It reacts readily with deoxyguanosine and DNA to form aldehyde-derived DNA adducts.{28539}

Size	500 µg
Shipping	dry ice
CAS Number	22644-96-8
Molecular Formula	C₁₆H₃₀O
SMILES	O=C([H])/C=C/CCCCCCCCCCCCC
Molecular Weight	238,4
Formulation	A crystalline solid
Purity	≥95%
Custom Code	2912.19
UNSPSC code	12352100

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

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