(?)-Gallocatechin

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(?)-Gallocatechin

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Cat No: 16944

Biochemicals - Natural Products

(−)-Gallocatechin ((−)-GC) is an epimer of (−)-epigallocatechin ((−)-EGC; Item No. 11809). They are flavan-3-ols and members of the catechin family of polyphenolic antioxidants found in green tea and other plant extracts.{23119} Both (−)-GC and (−)-EG...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

(2S,3R)-3,4-dihydro-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3,5,7-triol

Correlated keywords:

biochemical natural product antioxidant inflammation cancer inhibitor Alzheimer’s research inhibit flavonoid flavan-3-ol catechin family polyphenolic green tea plant extract epimer (-)-epigallocatechin EGC proliferation HCT-116 HCT116 SW-480 SW480 cell aggregation amyloid ? peptide in vitro increase temperature steaming leaves reduction reduce 2,3-cis isomers 2,3-trans (-)-Gallocatechol l-Gallocatechin

Product Overview:
(−)-Gallocatechin ((−)-GC) is an epimer of (−)-epigallocatechin ((−)-EGC; Item No. 11809). They are flavan-3-ols and members of the catechin family of polyphenolic antioxidants found in green tea and other plant extracts.{23119} Both (−)-GC and (−)-EGC are potent antioxidants and significantly inhibit the proliferation of HCT116 and SW480 cancer cells.{23115,27615,23119} (−)-GC also inhibits the aggregation of amyloid β peptide in vitro (IC50 = 17.5 µM).{27617} With increasing temperature, the steaming of green tea leaves results in the reduction of 2,3-cis isomers, like (−)-EGC, and an increase in 2,3-trans isomers, like (−)-GC.{27615,27616}

Size	1 mg
Shipping	dry ice
CAS Number	3371-27-5
Molecular Formula	C₁₅H₁₄O₇
SMILES	OC1=CC([C@H]2[C@H](O)CC3=C(O)C=C(O)C=C3O2)=CC(O)=C1O
Molecular Weight	306,3
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2932.99
UNSPSC code	12352100

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

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