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5-trans Latanoprost

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    5-<em>trans</em> Latanoprost
  • 5-<em>trans</em> Latanoprost
Cat No: 16813
Biochemicals - Lipids
Cayman

Latanoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug.{1107} 5-trans Latanoprost is an isomer of latanoprost wherein the double bond between carbons 5 and 6 has been changed from cis (Z) to trans ...

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Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • (5E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoic acid, 1-methylethyl ester
Correlated keywords:
  • eyes ophthalmology ophthalmological intraocular glaucoma isopropyl esters FP receptors agonists 5-trans-17-phenyl-13,14-dihydro-trinor-PGF2.alpha. 5-trans-17-phenyl-13,14-dihydro-trinor-PGF2alpha
Product Overview:
Latanoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug.{1107} 5-trans Latanoprost is an isomer of latanoprost wherein the double bond between carbons 5 and 6 has been changed from cis (Z) to trans (E). The trans isomer of latanoprost occurs as an impurity of between 2-5% in most commercial preparations of the bulk drug product. The present compound was prepared primarily as an analytical standard for detection and quantitation of this impurity. From what can be inferred from the study of other trans isomers of F-type prostaglandins, 5-trans latanoprost’s biological activity is likely to be similar to that of the cis isomer. However, there are no specific published reports on the biological activity, and on the intraocular hypotensive activity in particular, of 5-trans latanoprost.
Size 1 mg
Shipping dry ice
CAS Number 913258-34-1
Molecular Formula C26H40O5
SMILES O[C@@H]1[C@H](C/C=C/CCCC(OC(C)C)=O)[C@@H](CC[C@@H](O)CCC2=CC=CC=C2)[C@H](O)C1
Molecular Weight 432,6
Formulation A solution in methyl acetate
Purity ≥98%
Custom Code 3822.19
UNSPSC code 12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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ISO Guide 34:2009

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