Ribavirin

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Ribavirin

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Cat No: 16757

Ribavirin is an antiviral guanosine nucleoside analog.{29248,59186} Upon entry into cells, ribavirin is metabolized to an active triphosphate form that induces viral RNA chain termination and inhibits viral polymerases. It reduces replication in a pan...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

1-?-D-ribofuranosyl-1H-1,2,4-triazole-3-carboxamide

Correlated keywords:

66510-?90-?5 437710-?49-?1 anti viral Copegus Cotronak EBP 954 EBP954 ICN 1229 ICN1229 Meduna Megaribavirin NSC163039 Ravanex Rebetol Ribamide Ribamidil Ribasphere Ribavarin Ribavirin Tribavirin Vilona Viramid Virazole Virin Virizadole

Product Overview:
Ribavirin is an antiviral guanosine nucleoside analog.{29248,59186} Upon entry into cells, ribavirin is metabolized to an active triphosphate form that induces viral RNA chain termination and inhibits viral polymerases. It reduces replication in a panel of seven RNA and four DNA viruses in Vero cells (EC50s = 2-95 µg/ml).{59187} Ribavirin also reduces replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Vero cells (EC50 = 109.5 µM).{45843} Aerosol administration of ribavirin (30 mg/kg) reduces mortality in a mouse model of influenza A infection.{59188} Formulations containing ribavirin have been used in the treatment of respiratory syncytial virus (RSV), hepatitis C virus (HCV), and viral hemorrhagic fevers.

Size	250 mg
Shipping	dry ice
CAS Number	36791-04-5
Molecular Formula	C₈H₁₂N₄O₅
SMILES	OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2N=C(C(N)=O)N=C2)O1
Molecular Weight	244,2
Formulation	A crystalline solid
Purity	≥95%
Custom Code	2933.29
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.