2-Hydroxypropyl-?-cyclodextrin

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Cat No: 16169

Biochemicals - Carbohydrates

2-Hydroxypropyl-β-cyclodextrin (HP-β-CD) is a cyclic oligosaccharide containing seven D-(+)-glucopyranose units that is widely used to improve the aqueous solubility of various compounds, especially those containing a phenyl group.{26620,26621,23432} ...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

2-hydroxypropyl ethers ?-cyclodextrin

Correlated keywords:

complexation improved aqueous solubility cyclic oligosaccharides drugs delivery bioavailability HPs ? CDs HP?CDs glucopyranose D-(+)-glucopyranose improves compounds phenyls groups rings configurations circular glucose units torus shaped torus-shaped groups ethers linkages hollow interiors nonpolar non polar non-polar hydrophobic cavity cavities hydrophilic exteriors solutions molecules isolates isolation isolated aromatics water increases increased 94035-02-6 (2-hydroxypropyl)-?-cyclodextrin hydroxypropyl cylclodextrin discovery

Product Overview:
2-Hydroxypropyl-β-cyclodextrin (HP-β-CD) is a cyclic oligosaccharide containing seven D-(+)-glucopyranose units that is widely used to improve the aqueous solubility of various compounds, especially those containing a phenyl group.{26620,26621,23432} The circular arrangement of its glucose units produces a torus-shaped ring configuration in which the CH2 groups and ether linkages of the molecule face the hollow interior, resulting in a nonpolar, hydrophobic cavity and a polar, hydrophilic exterior. When combined in solution with other compounds, the nonpolar aromatic portions of that compound interact with the nonpolar interior of the HP-β-CD molecule, thus isolating the aromatic portion of the molecule from the water and thereby increasing its aqueous solubility.{26620,21228} HP-β-CD is a mixture containing HP-β-CD with variable hydroxypropyl group substitutions.

Size	1 g
Shipping	room temp.
CAS Number	128446-35-5
Molecular Formula	(C₆H₉O₅)₇(C₃H₇O)
SMILES	O[C@H]1[C@@](O[C@](O[C@H](COCC(O)C)[C@](O[C@](O[C@H](COCC(C)O)[C@](O[C@](O[C@H](COCC(O)C)[C@](O2)([H])[C@@H]3O)([H])[C@@H]3O)([H])[C@@H]4O)([H])[C@@H]4O)([H])[C@@H]5O)([H])[C@@H]5O)([H])[C@H](O[C@@](O[C@]([C@@H]6O)([H])[C@H](O[C@@](O[C@]([C@@H]7O)([H])[C@
Molecular Weight	1541,6
Formulation	A crystalline solid
Purity	≥95%
Custom Code	2909.60
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.