Oseltamivir (phosphate)

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Cat No: 16070

Oseltamivir is an antiviral prodrug targeted against the influenza viruses.{25827,25824} Once hydrolyzed in the liver to its active metabolite, oseltamivir acid (Item No. 15779), it can competitively inhibit viral neuraminidase (IC50s = 0.1-4.9 nM for...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

4R-(acetylamino)-5S-amino-3R-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid, ethyl ester, monophosphate

Correlated keywords:

332047-?25-?3 196618-13-0 antiviral anti viral anti-viral inhibits inhibitions inhibitors pro-drug pro drugs prodrug influenza neuraminidase A B viruses hydrolyzed active metabolites phosphates infectious GSs 4104 GS4104 GS-4104 fluvir Ro 64-0796/002 saiflu Ro64-0796/002 Ro-64-0796/002

Product Overview:
Oseltamivir is an antiviral prodrug targeted against the influenza viruses.{25827,25824} Once hydrolyzed in the liver to its active metabolite, oseltamivir acid (Item No. 15779), it can competitively inhibit viral neuraminidase (IC50s = 0.1-4.9 nM for influenza neuraminidases A and B), blocking the release of new viral particles from a host cell.{25825,25826,25830,25829,25828}

Size	100 mg
Shipping	dry ice
CAS Number	204255-11-8
Molecular Formula	C₁₆H₂₈N₂O₄ • H₃PO₄
SMILES	N[C@@H]1[C@@H](NC(C)=O)[C@H](OC(CC)CC)C=C(C(OCC)=O)C1.O=P(O)(O)O
Molecular Weight	410,4
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2922.19
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.